제갈경환Kyung Hwan Jegal
| 대구한의대학교 한의학과 한의학사 대구한의대학교 한의학과 한의학석사 대구한의대학교 한의학과 한의학박사 |
| 1: Cho IJ, Kim D, Kim EO, Jegal KH, Kim JK, Park SM, Zhao R, Ki SH, Kim SC, Ku SK. Cystine and Methionine Deficiency Promotes Ferroptosis by Inducing B-Cell Translocation Gene 1. Antioxidants (Basel). 2021 Sep 28;10(10):1543. doi: 10.3390/antiox10101543. PMID: 34679678; PMCID: PMC8532826. 2: Park SM, Kim JK, Kim EO, Jegal KH, Jung DH, Lee SG, Cho IJ, Kim S, Byun SH, Ku SK, Park CA, Lee CW, An WG, Kim SC, Zhao R. Hepatoprotective Effect of Pericarpium zanthoxyli Extract Is Mediated via Antagonism of Oxidative Stress. Evid Based Complement Alternat Med. 2020 Jul 9;2020:6761842. doi: 10.1155/2020/6761842. PMID: 32695211; PMCID: PMC7368226. 3: Jegal KH, Kim EO, Kim JK, Park SM, Jung DH, Lee GH, Ki SH, Byun SH, Ku SK, Cho IJ, Kim SC. Luteolin prevents liver from tunicamycin-induced endoplasmic reticulum stress via nuclear factor erythroid 2-related factor 2-dependent sestrin 2 induction. Toxicol Appl Pharmacol. 2020 Jul 15;399:115036. doi: 10.1016/j.taap.2020.115036. Epub 2020 May 11. PMID: 32407927. 4: Kim SJ, Jegal KH, Im JH, Park G, Kim S, Jeong HG, Cho IJ, Kang KW. Involvement of ER stress and reactive oxygen species generation in anti-cancer effect of CKD-516 for lung cancer. Cancer Chemother Pharmacol. 2020 Apr;85(4):685-697. doi: 10.1007/s00280-020-04043-x. Epub 2020 Mar 11. PMID: 32157413. 5: Kim JK, Han NR, Park SM, Jegal KH, Jung JY, Jung EH, Kim EO, Kim D, Jung DH, Lee JR, Park CA, Ku SK, Cho IJ, Kim SC. Hemistepsin A alleviates liver fibrosis by inducing apoptosis of activated hepatic stellate cells via inhibition of nuclear factor-κB and Akt. Food Chem Toxicol. 2020 Jan;135:111044. doi: 10.1016/j.fct.2019.111044. Epub 2019 Dec 9. PMID: 31830547. 6: Yang JH, Kim KM, Cho SS, Shin SM, Ka SO, Na CS, Park BH, Jegal KH, Kim JK, Ku SK, Lee HJ, Park SG, Cho IJ, Ki SH. Inhibitory Effect of Sestrin 2 on Hepatic Stellate Cell Activation and Liver Fibrosis. Antioxid Redox Signal. 2019 Jul 20;31(3):243-259. doi: 10.1089/ars.2018.7559. Epub 2019 Apr 24. PMID: 30909713. 7: Park SM, Lee TH, Zhao R, Kim YS, Jung JY, Park CA, Jegal KH, Ku SK, Kim JK, Lee CW, Kim YW, Cho IJ, An WG, Kim SC. Amelioration of inflammatory responses by Socheongryong-Tang, a traditional herbal medicine, in RAW 264.7 cells and rats. Int J Mol Med. 2018 May;41(5):2771-2783. doi: 10.3892/ijmm.2018.3465. Epub 2018 Feb 6. PMID: 29436586; PMCID: PMC5846657. 8: Park SM, Min BG, Jung JY, Jegal KH, Lee CW, Kim KY, Kim YW, Choi YW, Cho IJ, Ku SK, Kim SC. Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo. BMC Complement Altern Med. 2018 Jan 19;18(1):20. doi: 10.1186/s12906-018-2088-x. PMID: 29351747; PMCID: PMC5775528. 9: Lee C, Chun W, Zhao R, Kim YD, Nam MM, Jung DH, Cho IJ, Jegal KH, Lee TH, Kim YW, Park SM, Ju SA, Lee CW, Kim SC, An WG. Anticancer effects of an extract from the scallop Patinopecten yessoensis on MCF-7 human breast carcinoma cells. Oncol Lett. 2017 Aug;14(2):2207-2217. doi: 10.3892/ol.2017.6424. Epub 2017 Jun 20. PMID: 28789443; PMCID: PMC5530092. 10: Park SM, Jung EH, Kim JK, Jegal KH, Park CA, Cho IJ, Kim SC. 20S-Protopanaxadiol, an aglycosylated ginsenoside metabolite, induces hepatic stellate cell apoptosis through liver kinase B1-AMP-activated protein kinase activation. J Ginseng Res. 2017 Jul;41(3):392-402. doi: 10.1016/j.jgr.2017.01.012. Epub 2017 Jan 25. PMID: 28701883; PMCID: PMC5489770. 11: Jung JY, Lee CW, Park SM, Jegal KH, Kim JK, Park CA, Cho IJ, Jung DH, An WG, Ku SK, Zhao R, Kim SC. Activation of AMPK by Buddleja officinalis Maxim. Flower Extract Contributes to Protecting Hepatocytes from Oxidative Stress. Evid Based Complement Alternat Med. 2017;2017:9253462. doi: 10.1155/2017/9253462. Epub 2017 Apr 3. PMID: 28473864; PMCID: PMC5394415. 12: Jegal KH, Park SM, Cho SS, Byun SH, Ku SK, Kim SC, Ki SH, Cho IJ. Activating transcription factor 6-dependent sestrin 2 induction ameliorates ER stress- mediated liver injury. Biochim Biophys Acta Mol Cell Res. 2017 Jul;1864(7):1295-1307. doi: 10.1016/j.bbamcr.2017.04.010. Epub 2017 Apr 19. PMID: 28433684. 13: Jegal KH, Ko HL, Park SM, Byun SH, Kang KW, Cho IJ, Kim SC. Eupatilin induces Sestrin2-dependent autophagy to prevent oxidative stress. Apoptosis. 2016 May;21(5):642-56. doi: 10.1007/s10495-016-1233-6. PMID: 27015669. 14: Lee CW, Park SM, Zhao R, Lee C, Chun W, Son Y, Kim SH, Jung JY, Jegal KH, Cho IJ, Ku SK, Kim YW, Ju SA, Kim SC, An WG. Hederagenin, a major component of Clematis mandshurica Ruprecht root, attenuates inflammatory responses in RAW 264.7 cells and in mice. Int Immunopharmacol. 2015 Dec;29(2):528-537. doi: 10.1016/j.intimp.2015.10.002. Epub 2015 Oct 23. PMID: 26481049. 15: Choi HY, Lee JH, Jegal KH, Cho IJ, Kim YW, Kim SC. Oxyresveratrol abrogates oxidative stress by activating ERK-Nrf2 pathway in the liver. Chem Biol Interact. 2016 Feb 5;245:110-21. doi: 10.1016/j.cbi.2015.06.024. Epub 2015 Jun 20. PMID: 26102008. 16: Lee JH, Jung JY, Jang EJ, Jegal KH, Moon SY, Ku SK, Kang SH, Cho IJ, Park SJ, Lee JR, Zhao RJ, Kim SC, Kim YW. Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway. Exp Biol Med (Maywood). 2015 Apr;240(4):508-18. doi: 10.1177/1535370214547123. Epub 2014 Aug 14. PMID: 25125496; PMCID: PMC4935380. 17: Lee CW, Park SM, Kim YS, Jegal KH, Lee JR, Cho IJ, Ku SK, Lee JY, Ahn YT, Son Y, Ju SA, Kim SC, An WG. Biomolecular evidence of anti-inflammatory effects by Clematis mandshurica Ruprecht root extract in rodent cells. J Ethnopharmacol. 2014 Sep 11;155(2):1141-55. doi: 10.1016/j.jep.2014.06.048. Epub 2014 Jun 27. PMID: 24975194. 18: Hwangbo M, Jung JY, Ki SH, Park SM, Jegal KH, Cho IJ, Lee JH, Kang SH, Park SD, Ku SK, Kim SC, Zhao RJ, Jee SY, Kim YW. U-Bang-Haequi Tang: A Herbal Prescription that Prevents Acute Inflammation through Inhibition of NF-κB- Mediated Inducible Nitric Oxide Synthase. Evid Based Complement Alternat Med. 2014;2014:542825. doi: 10.1155/2014/542825. Epub 2014 May 15. PMID: 24959187; PMCID: PMC4052510. 19: Yang JH, Kim SC, Shin BY, Jin SH, Jo MJ, Jegal KH, Kim YW, Lee JR, Ku SK, Cho IJ, Ki SH. O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation. Food Chem Toxicol. 2013 Sep;59:362-72. doi: 10.1016/j.fct.2013.05.049. Epub 2013 Jun 15. PMID: 23774260. |
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2012.3~2017.2 대구한의대 한의학과 한의학조교 2018.5.~2019.2.서울대학교 종합약학연구소 연구원 2019.3.~2020.3.서울대학교 약학대학 post-doc 2020.3. ~ 2021.12.한국한의학연구원 선임연구원 |
