김상찬Kim Sang Chan
| 학교명 | 전공 | 학위 |
|---|---|---|
| 대구한의대학교 | 한의학 | 학사 |
| 대구한의대학교 | 한의학 | 석사 |
| 대구한의대학교 | 한의학 | 박사 |
| 논문명 | 발표년도 | 게재지 |
|---|---|---|
| Sipjeondaebo-tang Alleviates Oxidative Stress-Mediated Liver Injury through Activation of the CaMKK2-AMPK Signaling Pathway. | 2018 | Evid Based Complement Alternat Med |
| Salinomycin ameliorates oxidative hepatic damage through AMP-activated protein kinase, facilitating autophagy | 2018 | Toxicol Appl Pharmacol |
| Aqueous Extract of Semen Ziziphi Spinosae Exerts Anxiolytic Effects during Nicotine Withdrawal via Improvement of Amygdaloid CRF/CRF1R Signaling | 2018 | Evid Based Complement Alternat Med |
| Deoxypodophyllotoxin in Anthriscus sylvestris alleviates fat accumulation in the liver via AMP-activated protein kinase, impeding SREBP-1c signal | 2018 | Chem Biol Interact |
| Effects of Gamisoyo-San Decoction, a Traditional Chinese Medicine, on Gastrointestinal Motility | 2018 | Digestion |
| Oxyresveratrol ameliorates nonalcoholic fatty liver disease by regulating hepatic lipogenesis and fatty acid oxidation through liver kinase B1 and AMP-activated protein kinase | 2018 | Chem Biol Interact |
| Modulation of Pacemaker Potentials in Murine Small Intestinal Interstitial Cells of Cajal by Gamisoyo-San, a Traditional Chinese Herbal Medicine | 2018 | Digestion |
| Fucoxanthin, the constituent of Laminaria japonica, triggers AMPK-mediated cytoprotection and autophagy in hepatocytes under oxidative stress | 2018 | BMC Complement Altern Med |
| Amelioration of inflammatory responses by Socheongryong-Tang, a traditional herbal medicine, in RAW 264.7 cells and rats | 2018 | Int J Mol Med |
| Epimedium koreanum Ameliorates Oxidative Stress-Mediated Liver Injury by Activating Nuclear Factor Erythroid 2-Related Factor 2 | 2018 | Am J Chin Med |
| Combination of Pelargonium sidoides and Coptis chinensis root inhibits nuclear factor kappa B-mediated inflammatory response in vitro and in vivo | 2018 | BMC Complement Altern Med |
| Blockade of nicotine sensitization by methanol extracts of Glycyrrhizae radix mediated via antagonism of accumbal oxidative stress | 2017 | BMC Complement Altern Med |
| Hemistepsin A ameliorates acute inflammation in macrophages via inhibition of nuclear factor-κB and activation of nuclear factor erythroid 2-related factor 2 | 2018 | Food Chem Toxicol |
| Manual Acupuncture at PC6 Ameliorates Acute Restraint Stress-Induced Anxiety in Rats by Normalizing Amygdaloid Noradrenergic Response | 2017 | Evid Based Complement Alternat Med |
| Tryptanthrin prevents oxidative stress-mediated apoptosis through AMP-activated protein kinase-dependent p38 mitogen-activated protein kinase activation | 2017 | Arch Pharm Res |
| Anticancer effects of an extract from the scallop Patinopecten yessoensis on MCF-7 human breast carcinoma cells | 2017 | Oncol Lett |
| 20S-Protopanaxadiol, an aglycosylated ginsenoside bolite, induces hepatic stellate cell apoptosis through liver kinase B1-AMP-activated protein kinase activation | 2017 | J Ginseng Res |
| Moutan Cortex Protects Hepatocytes against Oxidative Injury through AMP-Activated Protein Kinase Pathway | 2017 | Biol Pharm Bull |
| Activation of AMPK by Buddleja officinalis Maxim. Flower Extract Contributes to Protecting Hepatocytes from Oxidative Stress | 2017 | Evid Based Complement Alternat Med |
| Anti-inflammatory action of 2-carbomethoxy-2,3-epoxy-3-prenyl-1,4-naphthoquinone (CMEP-NQ) suppresses both the MyD88-dependent and TRIF-dependent pathways of TLR4 signaling in LPS-stimulated RAW264.7 cells | 2017 | J Ethnopharmacol |
| Activating tranion factor 6-dependent sestrin 2 induction ameliorates ER stress-mediated liver injury. | 2017 | Biochim Biophys Acta Mol Cell Res |
| Cheongsangbangpung-tang ameliorated the acute inflammatory response via the inhibition of NF-κB activation and MAPK phosphorylation. | 2017 | BMC Complement Altern Med |
| Liqustri lucidi Fructus inhibits hepatic injury and functions as an antioxidant by activation of AMP-activated protein kinase in vivo and in vitro. | 2017 | Chem Biol Interact |
| Suppressive effects of dabrafenib on endothelial protein C receptor shedding. | 2017 | Arch Pharm Res |
| Anti-vascular inflammatory effects of pentacyclic triterpenoids from Astilbe rivularis in vitro and in vivo. | 2017 | Chem Biol Interact |
| Saeng-Kankunbi-Tang () protects liver against oxidative damage through activation of ERK/Nrf2 pathway. | 2016 | Chin J Integr Med |
| Isorhamnetin attenuates liver fibrosis by inhibiting TGF-β/Smad signaling and relieving oxidative stress. | 2016 | Eur J Pharmacol |
| Eupatilin induces Sestrin2-dependent autophagy to prevent oxidative stress. | 2016 | Apoptosis |
| Hypothalamic Norepinephrine Mediates Acupunctural Effects on Hypothalamic-Pituitary-Adrenal Axis During Ethanol Withdrawal. | 2016 | J Acupunct Meridian Stud |
| Anti-inflammatory Steroid from Phragmitis rhizoma Modulates LPS-Mediated Signaling Through Inhibition of NF-κB Pathway. | 2016 | Inflammation |
| AMPK activation by liquiritigenin inhibited oxidative hepatic injury and mitochondrial dysfunction induced by nutrition deprivation as mediated with induction of farnesoid X receptor. | 2017 | Eur J Nutr |
| Isoliquiritigenin in licorice functions as a hepatic protectant by induction of antioxidant genes through extracellular signal-regulated kinase-mediated NF-E2-related factor-2 signaling pathway. | 2016 | Eur J Nutr |
| Oxyresveratrol abrogates oxidative stress by activating ERK-Nrf2 pathway in the liver. | 2016 | Chem Biol Interact |
| Hederagenin, a major component of Clematis mandshurica Ruprecht root, attenuates inflammatory responses in RAW 264.7 cells and in mice. | 2015 | Int Immunopharmacol |
| The traditional herbal medicine, Ge-Gen-Tang, inhibits pacemaker potentials by nitric oxide/cGMP dependent ATP-sensitive K(+) channels in cultured interstitial cells of Cajal from mouse small intestine. | 2015 | J Ethnopharmacol |
| The tegmental-accumbal dopaminergic system mediates the anxiolytic effect of acupuncture during ethanol withdrawal. | 2015 | Neurosci Lett |
| Tacrine, an oral acetylcholinesterase inhibitor, induced hepatic oxidative damage, which was blocked by liquiritigenin through GSK3-beta inhibition. | 2015 | Biol Pharm Bull |
| Sauchinone attenuates liver fibrosis and hepatic stellate cell activation through TGF-β/Smad signaling pathway. | 2015 | Chem Biol Interact |
| Isoliquiritigenin attenuates oxidative hepatic damage induced by carbon tetrachloride with or without buthionine sulfoximine. | 2015 | Chem Biol Interact |
| Glycyrrhizae radix methanol extract attenuates methamphetamine-induced locomotor sensitization and conditioned place preference. | 2014 | Evid Based Complement Alternat Med |
| Korean Red Ginseng attenuates anxiety-like behavior during ethanol withdrawal in rats. | 2014 | J Ginseng Res |
| Tryptanthrin protects hepatocytes against oxidative stress via activation of the extracellular signal-regulated kinase/NF-E2-related factor 2 pathway. | 2014 | Biol Pharm Bull |
| Combination of honokiol and magnolol inhibits hepatic steatosis through AMPK-SREBP-1 c pathway. | 2015 | Exp Biol Med |
| Biomolecular evidence of anti-inflammatory effects by Clematis mandshurica Ruprecht root extract in rodent cells. | 2014 | J Ethnopharmacol |
| AMPK activation by isorhamnetin protects hepatocytes against oxidative stress and mitochondrial dysfunction. | 2014 | Eur J Pharmacol |
| U-Bang-Haequi Tang: A Herbal Preion that Prevents Acute Inflammation through Inhibition of NF-κB-Mediated Inducible Nitric Oxide Synthase. | 2014 | Evid Based Complement Alternat Med |
| Effects of the aqueous extract of Schizandra chinensis fruit on ethanol withdrawal-induced anxiety in rats. | 2014 | Chin Med J (Engl) |
| Curcumin significantly enhances dual PI3K/Akt and mTOR inhibitor NVP-BEZ235-induced apoptosis in human renal carcinoma Caki cells through down-regulation of p53-dependent Bcl-2 and inhibition of Mcl-1 protein stability. | 2014 | PLoS One |
| Involvement of amygdaloid neuropeptide Y in the anxiolytic effects of acupuncture during ethanol withdrawal in rats. | 2014 | Neurosci Lett |
| Role of 6-shogaol in tert -butyl hydroperoxide-induced apoptosis of HepG2 cells. | 2014 | Pharmacology |
| The antioxidant effects of isorhamnetin contribute to inhibit COX-2 in response to inflammation: a potential role of HO-1. | 2014 | Inflammation |
| Inhibition of Acute Phase Inflammation by Laminaria japonica through Regulation of iNOS-NF- κ B Pathway. | 2013 | Evid Based Complement Alternat Med |
| Methanol Extract of Artemisia apiacea Hance Attenuates the Expression of Inflammatory Mediators via NF- κ B Inactivation. | 2013 | Evid Based Complement Alternat Med |
| Isorhamnetin protects against oxidative stress by activating Nrf2 and inducing the of its target genes. | 2014 | Toxicol Appl Pharmacol |
| Amygdaloid corticotropin-releasing factor is involved in the anxiolytic effect of acupuncture during ethanol withdrawal in rats. | 2013 | J Acupunct Meridian Stud |
| O-Methylated flavonol isorhamnetin prevents acute inflammation through blocking of NF-κB activation. | 2013 | Food Chem Toxicol |
| Red ginseng extract protects against carbon tetrachloride-induced liver fibrosis. | 2013 | J Ginseng Res |
| Protective effects of Korean red ginseng extract on cadmium-induced hepatic toxicity in rats. | 2013 | J Ginseng Res |
| Inhibitory effects of traditional herbal formula pyungwi-san on inflammatory response in vitro and in vivo. | 2013 | Evid Based Complement Alternat Med |
| Roots of Erigeron annuus Attenuate Acute Inflammation as Mediated with the Inhibition of NF- κ B-Associated Nitric Oxide and Prostaglandin E2 production. | 2013 | Evid Based Complement Alternat Med |
| Red ginseng abrogates oxidative stress via mitochondria protection mediated by LKB1-AMPK pathway. | 2013 | BMC Complement Altern Med |
| Bojesodok-eum, a Herbal Preion, Ameliorates Acute Inflammation in Association with the Inhibition of NF-κB-Mediated Nitric Oxide and ProInflammatory Cytokine Production. | 2012 | Evid Based Complement Alternat Med |
| Anti-inflammatory effects of bangpungtongsung-san, a traditional herbal preion. | 2012 | Evid Based Complement Alternat Med |
| Antioxidant and Protective Effects of Bupleurum falcatum on the L-Thyroxine-Induced Hyperthyroidism in Rats. | 2012 | Evid Based Complement Alternat Med |
| Acupuncture Attenuates Anxiety-Like Behavior by Normalizing Amygdaloid Catecholamines during Ethanol Withdrawal in Rats. | 2011 | Evid Based Complement Alternat Med |
| Inhibition of liver X receptor-α-dependent hepatic steatosis by isoliquiritigenin, a licorice antioxidant flavonoid, as mediated by JNK1 inhibition. | 2010 | Free Radic Biol Med |
| Inhibition of SREBP-1c-mediated hepatic steatosis and oxidative stress by sauchinone, an AMPK-activating lignan in Saururus chinensis. | 2010 | Free Radic Biol Med |
| Efficacy of sauchinone as a novel AMPK-activating lignan for preventing iron-induced oxidative stress and liver injury. | 2009 | Free Radic Biol Med |
| Proteomic and behavioral analysis of response to isoliquiritigenin in brains of acute cocaine treated rats. | 2008 | J Proteome Res |
| Liquiritigenin, a flavonoid aglycone from licorice, has a choleretic effect and the ability to induce hepatic transporters and phase-II enzymes. | 2008 | Am J Physiol Gastrointest Liver Physiol |
| A new cytotoxic guaianolide from Chrysanthemum boreale. | 2009 | Fitoterapia |
| Hepatoprotective Activity of Licorice Water Extract against Cadmium-induced Toxicity in Rats. | 2009 | Evid Based Complement Alternat Med |
| Cytoprotective Activity of Glycyrrhizae radix Extract Against Arsenite-induced Cytotoxicity. | 2008 | Evid Based Complement Alternat Med |
| Sopungyangjae-tang inhibits development of dermatitis in nc/nga mice. | 2008 | Evid Based Complement Alternat Med |
| Isoliquiritigenin suppresses cocaine-induced extracellular dopamine release in rat brain through GABA(B) receptor. | 2008 | Eur J Pharmacol |
| Anti-inflammatory activity of the methanol extract of moutan cortex in LPS-activated Raw264.7 cells. | 2007 | Evid Based Complement Alternat Med |
| Ostreae Testa prevent ovariectomy-induced bone loss in mice by osteoblast activations. | 2007 | J Ethnopharmacol |
| Differential inhibitory effects of baicalein and baicalin on LPS-induced cyclooxygenase-2 through inhibition of C/EBPbeta DNA- activity. | 2006 | Immunobiology |
| Liquiritigenin, an aglycone of liquiritin in Glycyrrhizae radix, prevents acute liver injuries in rats induced by acetaminophen with or without buthionine sulfoximine. | 2006 | Chem Biol Interact |
| The essential oil from Angelica gigas NAKAI suppresses nicotine sensitization. | 2005 | Biol Pharm Bull |
| Genetic identification of Panax ginseng and Panax quinquefolius by pyrosequencing methods. | 2005 | Biosci Biotechnol Biochem |
| Up-regulation of human beta-defensin 2 by interleukin-1beta in A549 cells: involvement of PI3K, PKC, p38 MAPK, JNK, and NF-kappaB. | 2004 | Biochem Biophys Res Commun |
| Cytoprotective effects of Glycyrrhizae radix extract and its active component liquiritigenin against cadmium-induced toxicity (effects on bad translocation and cytochrome c-mediated PARP cleavage). | 2004 | Toxicology |
| Cadmium-induced non-apoptotic cell death mediated by oxidative stress under the condition of sulfhydryl deficiency. | 2003 | Toxicol Lett |
| 특허명 | 등록년도 | 등록번호 |
|---|---|---|
| 매괴화 추출물을 유효성분으로 포함하는 간질환의 예방 또는 치료용 조성물 | 2018 | 10-1898411-00-00 |
| 천초 추출물을 유효성분으로 포함하는 간질환의 예방 또는 치료용 조성물 | 2018 | 10-1892381-00-00 |
| 부평초 추출물을 유효성분으로 포함하는 간질환의 예방 또는 치료용 조성물 | 2017 | 10-1786180-00-00 |
| 개불 추출물을 함유하는 의약 조성물 | 2013 | 10-1276426-00-00 |
| 애엽 추출물을 유효성분으로 함유하는 두발 보호 화장료 조성물 | 2013 | 10-1239516-00-00 |
| 뽕나무 추출물을 유효성분으로 함유하는 간경화증의 예방 및 치료용 조성물 | 2012 | 10-1215797-00-00 |
| 항균 활성을 나타내는 김 추출물을 유효성분으로 함유하는 화장료 조성물 | 2012 | 10-1203273-00-00 |
| 한국산 당귀로부터 추출분리되는 저급알콜용매 가용추출물을 포함하는 니코틴 중독 및 금단증상의 예방 및 치료용 약학조성물 | 2012 | JP-5022901 |
| 계혈등 추출물을 함유한 간질환의 치료 및 예방용 조성물 | 2012 | 10-1146861-00-00 |
| 금은화추출물을 유효성분으로 함유하는 약물 중독 및 금단증상의 예방 및 치료용 조성물 | 2011 | 10-1059282-00-00 |
| 약효가 증강된 현호색 추출물, 그 제조방법 및 그를함유하는 조성물 | 2011 | 10-1059359-00-00 |
| 현호색 추출물 또는 이로부터 분리되는디하이드로코리달린을 유효성분으로 함유하는 충치의 예방및 치료용 조성물 | 2010 | 10-0999597-00-00 |
| 나복자추출물을 유효성분으로 함유하는 고지혈증 또는 비만의 예방 및 치료용 조성물 | 2010 | 10-0967813-00-00 |
| 복합생약 추출물을 유효성분으로 함유하는 우울증 예방 및 치료용 약학 조성물 | 2009 | 10-0881368-00-00 |
| 감초로부터 분리된 이소리퀴리티게닌을 유효성분으로함유하는 약물 중독 및 금단 증상의 예방 및 치료용 조성물 | 2009 | 10-0881369-00-00 |
| 감초 추출물 또는 이로부터 분리되는 리퀴리티게닌을 유효성분으로 함유하는 약물중독 및 금단 증상의 예방 및 치료를 위한 조성물 | 2008 | 10-0815868-00-00 |
| 제한효소절편길이 다형성법을 이용한 녹용의 종간 유전자 감별 키트 | 2007 | 10-0765412-00-00 |
| 피부보습 및 향균 효과를 갖는 황금 및 황련 추출물을 함유하는 화장료 조성물 | 2007 | 10-0723370-00-00 |
| 당귀의 종간 유전자 감별 키트 | 2007 | 10-0720864-00-00 |
| 청대추 추출물을 포함하는 비만의 치료 및 예방용 조성물 | 2007 | 10-0686362-00-00 |
| 니코틴중독 및 금단증상의 예방 및 치료를 위한 천초근추출물을 함유하는 조성물 | 2007 | 10-0676403-00-00 |
| 파이로시권싱법을 이용한 녹용의 종간 유전자 감별 키트 | 2007 | 10-0673071-00-00 |
| 방풍의 종간 유전자 감별 키트 | 2007 | 10-0673069-00-00 |
| 실시간 PCR법을 이용한 인삼의 종간 유전자 감별 방법 | 2007 | 10-0673070-00-00 |
| 목통의 종간 유전자 감별 방법 | 2007 | 10-0673067-00-00 |
| 인삼의 종간 유전자 감별 방법 | 2007 | 10-0673066-00-00 |
| 중독 및 금단 증상의 예방 및 치료를 위한 천초근 추출물 및 분획물을 함유하는 조성물 | 2006 | 10-0663844-00-00 |
| 니코틴 중독 및 금단증산의 예방 및 치료를 위한 산조인 추출물을 함유하는 조성물 | 2006 | 10-0663181-00-00 |
| 목통의 종간 유전자 감별 키트 | 2006 | 10-0610313-00-00 |
| 인삼의 종간 유전자 감별 키트 | 2006 | 10-0610312-00-00 |
| 한국산 당귀로부터 추출분리되는 저급알콜용매 가용추출물을 포함하는 니코틴 중독 및 금단증상의 에방 및 치료용 약한 조성물 | 2006 | 10-0571853-00-00 |
| 당귀로부터 추출분리되는 정유 분획물을 포함하는 니코틴중독 및 금단증상의 예방 및 치료용 약학 조성물 | 2006 | 10-0571850-00-00 |
| A COMPOSITION COMPRISING THE PURIFIED ESSENTIAL OIL EXTRACT AND LOWER ALCOHOL SOLUBLE EXTRACT ISOLATED FROM ANGELICA GIGAS FOR THE PREVENTION AND TREATMENT OF NICOTINE ADDICTION AND WITHDRAWAL SYMPTOM | 2006 | wo-2006-028344 |
| AMETHODFORGENETICIDENTIFICATIONOFGINSENGSPECIESANDTHEKITUSINGTHEREBY | 2006 | wo-2006-016762 |
| 감초추출물또는리퀴리티게닌을포함하는중금속 중독으로 인한 질환의 치료 및 예방용 조성물 | 2006 | 10-0543257-00-00 |
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2018.08-2019.08 : KFDA (정책연구심의위원) 2018.02-2019.02 : 제주한의약연구원 (한방의료 자문위원) 2017.12-2017.12 : 대구창조경제연구회 (바이오 소재산업 발전방안 포럼 – 지정토론) 2016.03-2018.03 : KFDA (정책자문위원) 2014.12-2014.12 : 전남한방산업진흥원 (약효표준화 사업 자문위원) 2014.04-2014.04 : KFDA 식품의약품안전평가원 (한약 혼합단미엑스제 표준기재안 자문위원) 2013.01-2013.12 : KFDA 식품의약품안전평가원 (정책연구용역 심의위원) 2013.01-2013.12 : 한국한방산업진흥원 (천연물물질은행구축사업 자문위원) 2008.01-2014.07 : KFDA (중앙약사심의위원) 2001.03-2001.12 : 대한한의사협회 (제11차 ICOM 자문단) 2000.07-2001.02 : 한국보건의료인국가시험원 (한약사국시 문항개발정리위원) 2000.02-2000.02 : 한국보건의료인국가시험원 (한약사국가시험 시험위원) 1999.08-1999.08 : 한국보건의료인국가시험원 (한약사국시 문항개발정리위원) |
